Two persons were killed and another was wounded in a blast of a hand-grenade near a cafe in this ancient city on Friday, security sources said. The sources said the explosion occurred, early today, in front of the cafe in the district of Esenler in the European sector of the city. Policemen hurriedly sealed off the scene, while medics transported the wounded to hospital. The explosion occurred two days ahead of the conference for Syria\'s friends, due to involve representatives of more than 80 European and Arab states.